A dolescence is a critical phase in the search for self-identity, significantly impacting mental health. The 2019 WHO report notes that 301 million individuals experience anxiety disorders, with 58 million being children and adolescents. The relationship between physical fitness and mental health, particularly anxiety disorders, has been the focus of several studies.METHODThis research aims to investigate the relationship between physical fitness and anxiety levels in female adolescents (aged 16-18 years) at SMA Negeri 78 Jakarta. An analytical cross-sectional observational method was employed using simple random sampling of students in grades X and XI. Data were analyzed using the Fisher\'s Test in SPSS version 25.RESULTSThe majority of respondents were 16 years old (71.6%), had poor fitness levels (89.9%), and experienced mild to moderate anxiety (52.3%). Fisher\'s Test analysis in SPSS version 25 did not reveal a significant relationship between fitness and anxiety levels (p=0.628).CONCLUSIONThis study concludes that there is no significant relationship between physical fitness and anxiety levels in female adolescents at SMA Negeri 78 Jakarta. These findings contribute to understanding the factors influencing the mental health of adolescents.