Efektivitas ekstrak daun pepaya (carica papaya) terhadap hambatan endokarditis infektif pasca pencabutan gigi (Laporan penelitian)
D aun pepaya (carica papaya) sebagai obat herbal telah dikenal dapat mengobati banyak penyakit pada dunia kedokteran, tetapi jarang pada kedokteran gigi. Penelitian ini untuk melihat daya hambat C.papaya terhadap streptococcus sanguinis in vitro. Pembuatan ekstrak C.pepaya dilakukan dengan teknik maserasi dan distilasi untuk mendapatkan senyawa antibakteri. Uji antibakteri terhadap S. sanguinis dilakukan melalui metode difusi sumuran dengan media agar darah. Hasil: menyatakan bahwa setiap konsentrasi ekstrak memiliki daya hambat terhadap perrumbuhan bakteri streptococcus sanguinis in vitro. dan menunjukan adanya perbedaan yang bermakna (p< 0.05) antara masing-masing kelompok konsentrasi ( 100%, 80%, 60%, 40%,20%), serta terdapat perbandingan bervariasi antara konsentrasi ekstrak C. papaya dengan zona hambat pertumbuhan streptococcus sanguitis.
P apaya leaf (carica pappaya) asan herbal medicine has been known to rtreat many disease in the medical world, but rerely in the world of dentistry. This study used the bacterium streptococcus sanguinis which is a major cause of infective endocarditis after tooth extraction. The purpose of this study to see the effect of C,papaya against S.sanguinis in vitro.C. papaya extracted with maseration and distilation techniques to obtain antibakterial compounds, Anatibacterial test against S.sanguinis done through diffusion method with blood agar media. the results of this study states that any concentration of the extract had inhibitory effect on the growth of streptococcus sanguinis in vitro. This study showed a significant diffrerence (p<; 0,05) between each group concentration (100%,80%,60%,40%, 20%), and there as varying ratio between the concentration of the extract of C.papaya extract with growth inhibition zone of S.sanguinis.