V aping has emerged as a prominent alternative to conventionalcigarette smoking. It has evolved into a prevalent trend embraced by individualsworldwide, particularly in Indonesia. The escalating prevalence of vaping may beassociated with prevailing societal perceptions. Several studies have demonstratedthat the components of vape can engender various health complications. However,substantial evidence is required to address inquiries regarding the impact of vapingon oral health, specifically pertaining to DMFT (decayed, missing, filled) and orallesions among users in Indonesia. Aim : This study aims to ascertain differences inDMFT and oral lesions, as well as perceptions among smokers and non-smokerswho vape at Universitas Trisakti. Methods : An analytical observational studyutilizing a cross-sectional design was conducted among university students. Theresearch encompassed examinations of DMFT and oral lesions, coupled with theadministration of perception questionnaires. Chi-square tests and the Rasch modelwere used to analyze the data. Results : No significant differences was observed inDMFT between the smoker and non-smoker vape groups (p=0.770). Conversely, asignificant difference (p<0.05) was found in oral lesions, including nicotinestomatitis, hyperkeratosis, smoker's melanosis, coated tongue, buccal linea alba,and leukoedema between the smoker and non-smoker vape groups. Vaping smokersespoused the perception that vape aerosol is less toxic (51.4%), vaping is moreaffordable (60.8%), vape flavors and aromas are appealing (97.3%), and vapingyields a pleasant oral scent (97.3%). Conclusion : Significant differences wereidentified in decayed, filled, nicotine stomatitis, hyperkeratosis, smoker'smelanosis, coated tongue, buccal linea alba, and leukoedema between smokers andnon-smokers who vape. Furthermore, disparities in perceptions were observedbetween smokers and non-smokers, with regard to the upsurge in vaping attributedto societal evolution and peer influence.