P T Van Melle Indonesia is one of the candy industries that uses sugar as the main raw material to produce high organic content with COD concentrations ranging from 10,000 - 30,000 mg / L.The processing used by PT VMI is a combination of anarobic (anaerobic EGSB / Estended Granular Sludge Blanket) and aerobic (extended aerartion) systems. Although the efficiency value reaches more than 90%, the final COD concentration ranges from 60 - 250 mg / L. Based on the Decree of the State Minister for the Environment No. KEP-51 / MENKLH / 10/1995 dated 23 October 1995 the quality standard of liquid waste for industrial activities, the maximum COD concentration for class I is 100 mg / L, so the results still exceed the established quality standards.In this study, the anaerobic process waste from PT Van Melle Indonesia will be treated aerobically using a different alternative system from the processing at PT VMI, the selected processing system uses Aerobic Hybrid which is a continuation of the Aerobic Hybrid process, so that the processing capability of the system can be found. this. Anaerobic Hybrid Reactor, which is a combination of two types of reactors (aerobic biofilter system and temispension system). This reactor is expected to reduce the weakness of one of the existing systems.Operational conditions that are carried out are using variations of hydraulic residence time 4, 6, 12, 18, and 24 hours, after obtaining the optimum residence time of the study, followed by variations in the initial load concentration of COD This aims to determine the effect on the efficiency of organic matter removal. Initial COD concentrations ranged from 1000 - 1500 mg / L.Td(hour) Coenstration COD Allowance for Cons. COD (%) VSS concentration pH TemperatureInlet (mg / L) Outlet (mg / L) Outlet (mg / L) Suspended (mg / L) Suspended Inlet Inlet Suspended Outlet24 1291 36 97.22 1194 2036 6.78 8.49 8.13 27.8 27.8 28.118 1197 62 94.78 673 1722 6.77 8.31 7.78 27.3 27.5 27.912 1282 86 93.31 782 1668 6.54 8.19 8.06 27.2 27.2 27.56 1391 126 91.02 1006 828 6.61 8.14 7.99 27.4 27.4 27.74 1205 134 88.79 427 710 6.66 8.03 8.02 27.4 27.4 27.7From the core study, the highest efficiency (97.22%) was achieved at a residence time of 24 hours. At the hydraulic residence time of 18 and 12 hours, the final COD concentrations of 62 mg / L and 86 mg / L still meet the quality standards set at 100 mg / L. And at the hydraulic residence time of 6 and 4 hours the final COD concentration was 126 mg / L and 134 mg / L had exceeded the established quality standards. Organic load ranges from 1.25 to 0.18 kg COD / m³ dayIn the load variation of the initial concentration of COD at the optimum hydraulic residence time of 12 hours, the variation of the initial COD concentration of 2000 mg / L and 4000 mg / L, respectively, with the final COD concentration of 163 mg / L, 250 mg / L had exceeded the class quality standard. II of 300 mg / L is allowed, at a concentration of 4000 mg / L the final COD concentration is 1230 mg / L, far exceeding the quality standard limits for groups I and II.From the results of the research, it can be seen that the rate of the removed organic load decreases with the less residual time of the waste in the reactor. This happens because the time used by microorganisms to decompose organic matter is reduced so that the organic waste that is removed is less.