DETAIL KOLEKSI

Efektivitas ekstrak kayu manis (cinnamomum zeylanicum) sebagai antibakteri terhadap treponema denticola


Oleh : Sabrina Auliya Hegar

Info Katalog

Nomor Panggil : 617.632 SAB e

Penerbit : FKG - Usakti

Kota Terbit : Jakarta

Tahun Terbit : 2024

Pembimbing 1 : Lies Zubardiah

Subyek : Periodontics

Kata Kunci : antibacterial, periodontitis, treponema denticola, cinnamomum zeylanicum extract.

Status Posting : Published

Status : Lengkap


File Repositori
No. Nama File Hal. Link
1. 2024_TA_SKG_040002000121_Halaman-Judul.pdf 12
2. 2024_TA_SKG_040002000121_Lembar-Pengesahan.pdf 8
3. 2024_TA_SKG_040002000121_Bab-1_Pendahuluan.pdf 4
4. 2024_TA_SKG_040002000121_Bab-2_Tinjauan-Pustaka.pdf 11
5. 2024_TA_SKG_040002000121_Bab-3_Kerangka-Teori,-Kerangka-Konsep-dan-Hipotesis.pdf 3
6. 2024_TA_SKG_040002000121_Bab-4_Metode-Penelitian.pdf 10
7. 2024_TA_SKG_040002000121_Bab-5_Hasil-Penelitian.pdf 6
8. 2024_TA_SKG_040002000121_Bab-6_Pembahasan.pdf 5
9. 2024_TA_SKG_040002000121_Bab-7_Kesimpulan-dan-Saran.pdf 1
10. 2024_TA_SKG_040002000121_Daftar-Pustaka.pdf 8
11. 2024_TA_SKG_040002000121_Lampiran.pdf 38

L atar Belakang: Periodontitis adalah penyakit radang gingiva (gingivitis) yangtidak dirawat. Bakteri penyebab periodontitis adalah bakteri jenis Gram negatifseperti Treponema denticola. Perawatan penyakit periodontal yang utama adalahmenghilangkan bakteri melalui program kontrol plak. Perawatan penyakitperiodontal dapat dilakukan dengan cara non-bedah seperti skeling, kontrol plak,pemberian obat kumur antibakteri, dan antibiotik sistemik. Kayu manis(Cinnamomum zeylanicum) terbukti memiliki kandungan senyawa yang bersifatantibakteri. Tujuan: Mengetahui efektivitas ekstrak kayu manis sebagai antibakteriterhadap Treponema denticola. Metode: Penelitian ini merupakan penelitianeksperimental laboratorium secara in vitro dengan metode mikrodilusi. Treponemadenticola dibiakkan selama 1 x 24 jam kemudian diberi ekstrak kayu manis dengankonsentrasi (100%, 50%, 25%, 12.5%, 6.25%, 3.125%), BHI-B sebagai kontrolnegatif dan klorheksidin 0,2% sebagai kontrol positif. Uji antibakteri didapatkandengan menghitung total koloni bakteri yang diperoleh menggunakan rumus rataratajumlah koloni. Data yang diperoleh dianalisis menggunakan uji normalitas, ujiANOVA satu jalan, dan uji Post-Hoc LSD. Hasil: Pada uji ekstrak kayu manisterhadap Treponema denticola didapat daya hambat minimal (MIC) padakonsentrasi 3.125% dan daya bunuh minimal (MBC) pada konsentrasi 100%.Kesimpulan: Ekstrak kayu manis efektif sebagai antibakteri terhadap Treponemadenticola.

B ackground: Periodontitis is an inflammatory disease of the gingiva (gingivitis)that is not treated. The bacteria that cause periodontitis are Gram negative bacteriasuch as Treponema denticola. The main treatment of periodontal disease is theelimination of bacteria through plaque control programs. Treatment of periodontaldisease can be done by non-surgical methods such as scaling, plaque control,antibacterial mouthwash, and systemic antibiotics. Cinnamon (Cinnamomumzeylanicum) is proven to contain compounds that are antibacterial. Purpose: toknowing the effectiveness of cinnamon extract as an antibacterial againstTreponema denticola. Method: This research is an in vitro experimental studyusing the microdilution method. Treponema denticola was cultured for 1 x 24 hoursthen given cinnamon extract with concentrations (100%, 50%, 25%, 12.5%, 6.25%,3.125%) BHI-B as a negative control and 0,2% chlorhexidine as a positive control.The antibacterial test was obtained by counting the total bacterial colonies obtainedby using the formula for the average total colony of bacterial colonies. The dataobtained were analyzed using the normality test, one-way ANOVA test, and ThePost-Hoc LSD test. Results: In the test of cinnamon extract against Treponemadenticola, minimum inhibitory concentration (MIC) was obtained at aconcentration 3.125% and minimum bactericidal concentration (MBC) at aconcentration 100%. Conclusion: Cinnamon extract is effective as an antibacterialagainst Treponema denticola.

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