Kadar komplemen C3 di dalam saliva penderita penyakit periodontal sebelum dan sesudah perawatan

DETAIL KOLEKSI

Kadar komplemen C3 di dalam saliva penderita penyakit periodontal sebelum dan sesudah perawatan

Oleh : Ermayanti

Info Katalog

Nomor Panggil : 617.632 ERM k

Penerbit : FKG - Usakti

Kota Terbit : Jakarta

Tahun Terbit : 2004

Pembimbing 1 : Boedi Oetomo Roeslan

Subyek : Periodontal diseases;Saliva

Kata Kunci : periodontal disease, C3, saliva, treatment

Status Posting : Published

Status : Lengkap

File Repositori

No.	Nama File	Hal.
1.	2004_TA_KG_04098066_Halaman-judul.pdf	15
2.	2004_TA_KG_04098066_Lembar-pengesahan.pdf	1
3.	2004_TA_KG_04098066_Bab-1-Pendahuluan.pdf	4
4.	2004_TA_KG_04098066_Bab-2-Tinjauan-pustaka.pdf	33
5.	2004_TA_KG_04098066_Bab-3-Kerangka-teori-dan-hipotesis.pdf	6
6.	2004_TA_KG_04098066_Bab-4-Metode-penelitian.pdf	21
7.	2004_TA_KG_04098066_Bab-5-Hasil-penelitian.pdf	6
8.	2004_TA_KG_04098066_Bab-6-Pembahasan.pdf	9
9.	2004_TA_KG_04098066_Bab-7-Kesimpulan-dan-saran.pdf	3
10.	2004_TA_KG_04098066_Daftar-pustaka.pdf	2
11.	2004_TA_KG_04098066_Lampiran.pdf	45

Abstrak
Abstract

P enyakit periodontal adalah kondisi patologis berupa peradangan pada gingiva, ligamen periodontal, sementum dan tulang alveolar. Di dalam cairan celah gusi penderita penyakit periodontal, C3 memiliki kadar yang tinggi. Oleh karena itu kadar C3 di dalam saliva penderita penyakit periodontal lebih tinggi dibandingkan kadar C3 pada saliva subjek yang tidak menderita penyakit periodontal.Setelah dilakukan perawatan, maka kondisi jaringan periodosium akan kembali normal, diduga kadar C3 pada saliva akan kembali turun. Berdasarkan hal tersebut, dilakukan penelitian untuk mengetahui apakah ada perbedaan kadar C3 sebelum dan sesudah perawatan . Sepuluh pasien yang didiagnosa mengalami penyakit periodontal dan akan dilakukan perawatan diambil salivanya, satu minggu setelah dilakukan perawatan pasien diambil kembali salivanya. Kadar C3 sebelum dan sesudah perawatan diukur dengan metode lmmunodifusi radial. Hasil uji-t menunjukkan bahwa tidak ada perbedaan yang bermakna (p>0,05)antara kadar C3 didalam saliva sebelum perawatan lebih tinggi (22,7 Â± 10,4 mg dl-1) dibandingkan dengan kadar C3 sesudah operasi (16,57Â±3,92 mg dl. 1). Berdasarkan hasil penelitian ini dapat disimpulkan bahwa kadar C3 di dalam saliva penderita penyakit periodontal akan mengalami penurunan setelah dilakukan perawatan.

P eriodontal disease is a pathologic condition with the inflammatory of gingiva, periodontal ligament, cementum and elveolar bone. Periodontal disease patients haved the C3 concentration higher on their intergingival fluid. It caused the C3 concentration on the saliva people who had periodontal disease was higher than others normal. After treatment, the condition of periodonsium tissue is getting back normal, so it can be predicted that C3 concentration on their saliva will be decreased. Based on this, a research to know about the difference of C3 concentration on the patient's saliva before and after treatment has done. This research took several samples to support the aim. Ten patients diagnosed have periodontal disease asked to be participant on this research. Therefore, the saliva for helping care before and after treatment was collected. A week after treatment, the saliva was collected again. C3 concentration of the saliva before and after surgery was measured by using Radial lmmunodiffusion method. T- tets showed that the C3 concentration before treatment was higher ( 22,7Â±10,4 mg dl-1) than after treatment (16,57Â±3,92 mg dL-\but there was no significant difference (p>0,05).From this research, it can be inffered that C3 concentration of the saliva of the periodontal disease patients will be decreased after doing treatment.