Y ogyakarta is one of the cities in Indonesia that is growing rapidly. The rapiddevelopment has resulted in the change of needs of life and of the standard ofliving in society, one of which is the need for beauty clinic. This change isespecially needed for career women who require beauty clinic to improve theirself-confidence. They need beauty clinics to treat their skin problems. That is whyin doing skin care treatment, they need a comfortable, secure, and relaxedatmosphere. Due to the increase needs for skin treatment at Kota Baru,Yogyakarta, there are many new beauty clinics have been established in theregion, such as, Erha Derma Center. There were several stage that should bedone in the process of designing the interior. The first, was review of literature,data collection in the form of field observation, and data analysis in order todevelop the concept design, followed by the visualization stage of the design in theform of drawings, presentations, and mockups.The application of Erha Derma Center interior design with the theme“Yogyakarta Decoration with a Modern Twist” was based on the aspect ofplanning the interior by considering the image of a clinic that is hygienic andclean. It is expected that consumers will feel comfortable both physically andpsychologically when they undertake skin treatments at beauty clinic