T itanium is very important because it is used for machine component materials in overcoming vibrations, as airplanes, spacecraft, leak-proof pipes and for medical equipment such as broken bone supports, dental implants. In this study, the flotation method was used for the acquisition of titanium from minerals in tin tailings. This study uses a particle size of -150 mesh with Na oleate reagent as a fother/collector and for Na chlorate as a depressant. Optimization was carried out with variations of Na oleate and Na chlorate reagents, flotation was carried out at pH 7 with a flotation machine speed of 900 rpm, temperature of 25 degrees with a total flotation time of 14 minutes. Optimization is carried out with the ratio of Na Chlorate : Na Oleate 1:10; 5:10; 10:10; 15:10 ratio of Na chlorate : Na oleate 10:3; 10:6; 10:9; 10:13. XRF results, the highest Titanium content of 1.52% at the smallest use of depressants in the depressant variation.The higher the depressant Ti level is smaller. The highest Ti content was 2.03% with the highest collector usage in collector variations. The higher the collector the Ti level is greater