A meloblastoma is a locally invasive benign tumor that can be found in the jaws. Even though the tumor takes only 1% of all tumor found in jaws, but it interests a lot of scientists because of its uniqueness and controversy. Originally, the tumors, assumed, arises from the cells rests of the enamel organ, the surface epithelium of the jaws, or from a developmental disturbance, epithelium of odontogenic cysts, such as dentigerous cysts, or from heterotopic epithelium in other parts of the body, particulary the pituitary glands, epithelial Malassez and Hertzwig. Clinically, the tumor attack people at the average age of 33 years with out predilection of sex and race. Radiographically , the tumor may appear as a unilocular, multilocular, peripheral, and malignant. Histologically, the tumors have six types: follicular, plexiform, acanthomatous, basal cells, granular cell, and desmoplastic. Generally, ameloblastoma often recurs under simple treatment and differential diagnosis can be limited to several entities in the three categories of jaws disease: odontogenic tumors, cysts, and benign non-odontogenic lesions.