T ourism sector has become increasingly influential as the source of foreign exchange earnings especially in the revenue sources of hotel sector. By the presence of hotels, a promising business called MICE (meeting, incentive, conference, and exhibition) has emerged. MICE has made positive and significant impact on the economy of Jakarta. Jakarta is a business destination and a place where domestic and global business people have their meetings. So, hotels are in great demand. Concerning this matter, The Media Hotel & Towers was designed with the issues of how to formulate the concept of hotel interior design which is in line with the missions and visions of the hotel, as well as the users’ characters. Moreover, the design should apply local Indonesian culture with modern and fashionable touch. The design aimed at providing inputs either data or the procedures of planning the interior of business hotel as well as introducing Indonesian culture by applying it to the hotel interior. The research design was carried out using a descriptive-qualitative method.The interior of The Media Hotel & Towers Business Hotel in South Jakarta was designed by promoting the theme of “Tree Shade in Balinese Culture” symbolically tailored to a tree and Balinese culture, the unique characteristics of The Media Hotel & Towers. These characteristics will present the image of elegant, cultured and warm. The theme and images will be combined together in classic style with contemporary attitude.