A Acute Respiratory Infection (ARI) is known as one of the leading cause of death in infant and children under five years old in developing countries. Most of the research in the developing countries shows 20-35% death in infant caused by ARI.Environmental sanitation such as cooking fuel, chimney, smoking habit inside the house, two or more people using the same bedroom, air ventilation condition, clean water sources, and the usage of mosquito repellent, are the factors that play the role in the occurrence of respiratory infections.METHODSThe study used analytic observational with cross sectional design including 190 infants that came to Puskesmas Kecamatan Mekar Baru, Tangerang. Data was collected by using subject’s medical records and questionnaires which include characteristics of the respondents, and the condition of environmental sanitation. Analysis of data is using statistical test.THE RESULTSFisher’s exact test analysis results show the value of correlation variables in the environmental sanitation part with ARI. The test shows P=0,031 for cooking fuel and P=0,002 for chimney, which can be concluded that there is a correlation between those variables with ARI, while smooking in the house, two or more people using same bedroom, air ventilation, clean water sources and the usage of mosquito repellent show no correlation with ARI.CONCLUSIONIn this study, a component of environmental sanitation such as cooking fuel, and chimneys have been associated with respiratory infections, while other environmental sanitation components such as smoking habit inside the house,two or more people using the same bedroom, air ventilation condition, clean waters sources, and the usage of the mosquito repellent have no correlation with ARI.