D Dysmenorrhea is abdominal pain that comes from uterine cramps that occur duringmenstruation. The number of women experiencing dysmenorrhea continues to increaseaccording to WHO, the prevalence of dysmenorrhea in Indonesia is 64.25%. There areseveral factors that can cause dysmenorrhea, including smoking, obesity, caffeineconsumption, period of menarche, and menstrual age. In pathophysical mechanisms,dysmenorrhea caused by increased disintegration of endometrial cells can secretePGF2α and stimulate myometrial hypertonus. Meanwhile, the pain caused bymyometrial hypercontraction can lead to vasoconstriction of blood vessels in the uteruswhich results in ischemia and sensitization of the uterine nerve roots. Dysmenorrhea isdivided into primary dysmenorrhea and secondary dysmenorrhea. Caffeineconsumption can also trigger pain because caffeine can lead to an increase inprostaglandins when intake is excessive. Uterine contractions increase when theproduction of prostaglandins is higher and triggers pain during menstruation(dysmenorrhea). Caffeine can also cause vasoconstriction of uterine blood vessels,which can aggravate dysmenorrhea. An increase in the incidence of dysmenorrhea canoccur when excess caffeine intake, which is more than 300 mg / day.