Efisiensi energi ruang bersih produksi obat Betalaktam pabrik farmasi
Info Katalog
File Repositori
Subyek : Clean rooms;Pharmaceutical technology - Quality control
Penerbit : FTI - Usakti
Kota Terbit : Jakarta
Tahun Terbit : 2016
Pembimbing 1 : Chalilullah Rangkuti
Kata Kunci : clean room, energy efficiency, particle, cooling load
Status Posting : Published
Status : Lengkap
File Repositori
| No. | Nama File | Hal. | Link |
|---|---|---|---|
| 1. | 2016_TS_MTM_161131001_Halaman-Judul.pdf | ||
| 2. | 2016_TS_MTM_161131001_Lembar-Pengesahan.pdf | -1 | |
| 3. | 2016_TS_MTM_161131001_Bab-1_Pendahuluan.pdf | -1 | |
| 4. | 2016_TS_MTM_161131001_Bab-2_Tinjauan-Pustaka.pdf |
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| 5. | 2016_TS_MTM_161131001_Bab-3_Metode-Penelitian.pdf |
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| 6. | 2016_TS_MTM_161131001_Bab-4_Pengumpulan-dan-pengolahan-data.pdf |
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| 7. | 2016_TS_MTM_161131001_Bab-5_Pembahasan-hasil-penelitian.pdf |
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| 8. | 2016_TS_MTM_161131001_Bab-6_Kesimpulan-dan-saran.pdf |
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| 9. | 2016_TS_MTM_161131001_Daftar-Pustaka.pdf | 2 | |
| 10. | 2016_TS_MTM_161131001_Lampiran.pdf |
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R Ruang bersih merupakan ruangan dimana jumlah partikel yang terdapat di daiamnya dikontrol. Selain partikel, ada beberapa parameter lainnya yang ikut dikontrol seperti temperatur udara, kelembaban udara, jumlah pertukaran udara dalam satu jam serta tekanan udara dalam ruangan. Ruang bersih diterapkan pada industri semikonduktor, industri farmasi dan industri kesehatan. Penelitian ini dilakukan pada sebuah pabrik farmasi. Kurangnya pemahaman akan persyaratan aliran udara dan adanya kekhawatiran tentang kebersihan dan persyaratan operasional, menyebabkan kecenderungan berlebihan dalam desain ruang bersih. Penelitian ini dimaksudkan untuk melihat unit yang terpasang di lapangan sudah memenuhi standard ruang bersih ataupun belum. Terlebih dahulu dilakukan identifikasi ruang bersih sesuai dengan standard BPOM, standard US FED STD 209E dan standard ISO no 14644. Metode perhitungan beban pendinginan menggunakan standard American Society of Heating, Refrigerating and Air Conditioning Engineers (ASHRAE). Dari hasil penelitian diperoleh beban pendinginan untuk 4 sistem tata udara yang sudah terpasang di lapangan sebesar 397.700 Btu/h sedangkan dari perhitungan ulang beban pendingin yang dibutuhkan 346.473 Btu/h teijadi penurunan sebesar 13%. Jika dikonversikan dengan biaya listrik bulanan dengan memperhitungkan LWBP dan WBP asumsi mesin produksi selama 24 jam maka biaya listrik dapat hemat 18% dari Rp100.527.482 menjadi Rp82.449.827. Return On Investment sebesar 3,65% dan Payback Period selama 28 bulan. Melalui penelitian ini, diharapkan industri farmasi dapat menekan biaya operasional produksi.
C Cleanroom is a room in which the number of particles contained in is controlled. In addition to the particles, there are several other parameters that are also controlled i.e air temperature, humidity, the number of air changes in an hour, and the air pressure in the room. The cleanroom is applied to the semiconductor, the pharmaceutical and healthcare industry. This research is conducted at a pharmaceutical factory. Lack of understanding of air flow requirements and their concerns on hygienic and operational requirements, causing excessive tendency in the design of a cleanroom. The aim of this study is to look wether the cleanrooms meets the requirement standard or not and to propose any changes to be taken as necessary. This is done firstly to identify a cleanroom in accordance with BPOM standard, US FED STD 209E standard the ISO no 14644 standard. The method of calculating the cooling load using standard American Society of Heating, Refrigerating and Air Conditioning Engineers (ASHRAE). The results were obtained for four cooling load HVAC systems available of 397.700 Btu/h while the recalculation of the required cooling load is 346.473 Btu/h; reduced by 1 3%. Converted to monthly electricity costs by taking into account the assumptions of WBP and LWBP and operating for 24 hours, the cost of electricity can be saved 18% to be Rp82.449.827. Return Of investment (ROI) amounted to 3,65% can be reached within a period of 28 months and is feasible to be conducted to reduce operating costs of production significantly.
