D Dyspepsia are divided into two types which are Functional Dyspepsia and Organic Dyspepsia. Functional Dyspepsia is defined to have an abnormality, but it does not have changes in the organs. Dyspepsia can be experienced with various stage of age, gender, and socio-economic. According to the Ministry of Health from the Republic of Indonesia in 2011, Dyspepsia is in the top ten list of the biggest disease that causes people to be hospitalized in 2010. The purpose of this research was to determined the relation of obesity with functional dyspepsia in the productive ages (15-64 years old). This research uses an observational method and an approach of cross-sectional. The observation that was conducted it needed 123 people to be a subject, these subject was taken at a Public Health Centre In South Jakarta, Lebak Bulus. The data was collected by interviewing those who volunteered in the public health center, the interview itself is based on the criteria that it is mentioned in the (Roma III) which includes questions around functional dyspepsia. Other than that, data of weight and height was collected from the subjekts to calculate the Body Mass Index. From all the data that was collected, analysis is conducted with using an analytical software, SPSS version 20 with the accuracy of 0,05. The bivariate analysis has shown an essential relation with obesity (p = 0.001) with functional dyspepsia. While there is an unessential relation with gender (p = 0.187), age (p = 0,0677), and occupation (p = 0.0373) with functional dyspepsia occurring at the productive age (15-64 years old). The univariate analysis has an outcome the majority age of 15 – 49 years old, that are woman, with a status of being employed, and obesity. This research has shown obesity have an effect towards when a functional dyspepsia occurs at the productive age (15-64 years old).