B ackgroundCardiovascular disease often starts with atherosclerosis which is closely related to arterial stiffness. Atherosclerosis as a trigger for cardiovascular disease has a prevalence of 36.2% in Indonesia. In 2008 the prevalence of obesity in women in the world reached 300 million, the results of previous studies showed a contradiction in the relationship of obesity and an increase in arterial stiffness. This study aims to assess the prevalence of arterial stiffness and waist circumference more than normal in college students and assessing the relationship between of arterial stiffness and waist size in female student.MethodsThe subjects of the study were students of the Faculty of Medicine with study design used was cross sectional. Waist circumference was assessed using a weist ruller and arterial stiffness was assessed using sphygmocor.. Chi-square test was used to see the relationship of waist circumference with arterial stiffness with the significance limit used was p <0.05.ResultsThe results of analysis female students who participated was 82 people, obtained the number of subjects with high arterial stiffness of 31 people. While the number of subjects with a waist circumference is more than normal of 29 people. There was a significant relationship between waist circumference and the incidence of arterial stiffness (p <0.001).ConclusionsThis study shows that there is a significant relationship between waist size and arterial stiffness in female student.