A ccquired immune deficiency syndrome (AIDS) is a multiple sympton of disease wich can damage to the human immune system cause by the human immunodeficiency Virus (HIV) Once infected with HIV, the patien does not directly cause clinical symptoms of AIDS, but the patien will have several stages of HIV infection until develop clinical symptoms of AIDS like opportunistic infections, neurological disease and cancer. there are three periodontal disease associated withinfrction of HIV,they are linear gingival erythema (LGE), Necrotizing Ulcerative periodontitis (NUP) periodontal disease can be connected to the damage of teh immune system patien. Etiology these diseases are opportunistic bacteria commonly found in patients with esrly stage is NUG, the last is NUP that became to the periodontal ligament and alveolar bone fast. Dentist is a firs profesional worker, who can recognize the clinical features and symptoms of periodontal disease associated with HIV infection by knowing the clinical description and the symptons of periodontal disease.