Pengaruh periodontitis terhadap keparahan covid-19 : scoping review

DETAIL KOLEKSI

Pengaruh periodontitis terhadap keparahan covid-19 : scoping review

Oleh : Sophie Ailsa Arthur

Info Katalog

Nomor Panggil : 617.632 SOP p

Penerbit : FKG - Usakti

Kota Terbit : Jakarta

Tahun Terbit : 2022

Pembimbing 1 : Marie Louisa

Subyek : Periodontics;Covid 19 (Disease)

Kata Kunci : periodontitis, COVID-19 severity, biomarker

Status Posting : Published

Status : Lengkap

File Repositori

No.	Nama File	Hal.	Link
1.	2022_TA_KG_040001800131_Halaman-Judul.pdf
2.	2022_TA_KG_040001800131_Lembar-Pengesahan.pdf
3.	2022_TA_KG_040001800131_Bab-1_Pendahuluan.pdf
4.	2022_TA_KG_040001800131_Bab-2_Tinjauan-Pustaka.pdf
5.	2022_TA_KG_040001800131_Bab-3_Kerangka-Teori.pdf
6.	2022_TA_KG_040001800131_Bab-4_Metode-Penelitian.pdf
7.	2022_TA_KG_040001800131_Bab-5_Hasil-Penelitian.pdf
8.	2022_TA_KG_040001800131_Bab-6_Pembahasan.pdf
9.	2022_TA_KG_040001800131_Bab-7_Kesimpulan-dan-Saran.pdf
10.	2022_TA_KG_040001800131_Daftar-Pustaka.pdf
11.	2022_TA_KG_040001800131_Lampiran.pdf

Abstrak
Abstract

L Latar Belakang : Pada Desember 2019, SARS-CoV-2 menyebar di Hubei, Cinamenyebabkan pandemi COVID-19. COVID-19 melibatkan berbagai organ,terutama pernapasan. Periodontitis adalah inflamasi kronis jaringan penyangga gigiyang dapat memiliki dampak pada respons imun sistemik, sehingga diduga dapatmempengaruhi keparahan COVID-19. Tujuan : Tujuan dari penelitian ini adalahmengetahui metode penelitian yang digunakan untuk mengetahui pengaruhperiodontitis terhadap keparahan COVID-19, serta parameter darah, biomarker danparameter keparahan COVID-19 yang berbeda pada pasien COVID-19 denganperiodontitis. Metode : Penelitian ini dilakukan dengan metode scoping reviewmenggunakan diagram PRISMA dengan kriteria populasi literatur terkait penderitaCOVID-19, konsep pengaruh periodontitis terhadap keparahan COVID-19, dankonteks global pada tiga basis data, yaitu PubMed, WILEY, dan Google Scholar.Hasil : Lima artikel sesuai kriteria inklusi menyatakan terdapat kaitan antaraperiodontitis dengan keparahan COVID-19, yang terdiri dari sebuah studi crosssectional, dua buah studi kohort, satu studi case control, dan satu studi retrospektifanalitik. Keparahan COVID-19 didasarkan beberapa parameter, yang meliputiparameter darah, biomarker, tingkat hospitalisasi, mortalitas, perawatan intensif,dan bantuan ventilasi. Kesimpulan : Metode penelitian yang telah dilakukan terkaithubungan periodontitis dengan keparahan COVID-19 meliputi studi case control,kohort, cross sectional, dan studi restropektif analitik. Periodontitis secara umummemperburuk gejala COVID-19 dengan meningkatkan D-dimer, troponin, CRP,pro-BNP, procalcitonin, HbA1c, ferritin, dan WBC sehingga meningkatkanhospitalisasi, mortalitas, perawatan intensif, dan bantuan ventilasi.

B Background : On December 2019, SARS-CoV-2 spread in Hubei, China causingCOVID-19 pandemic. COVID-19 affects various organs, especially respiration.Periodontitis is a chronic inflammation of periodontal tissues that inflicts impact onsystemic immune response, thus periodontitis is expected to contribute to COVID-19 severity. Aim : The aim of this research was to describe various researchmethods used to discover the the effects of periodontitis towards COVID-19severity, and to describe blood parameters, biomarkers, and COVID-19 severityparameters which are significantly disparate in COVID-19 patients withperiodontitis. Method : This scoping review was conducted using PRISMAdiagram consisted of literature related to COVID-19 patients as population,periodontitis impact towards COVID-19 severity as concept, and global as contextin three databases, namely PubMed, WILEY, and Google Scholar. Result : Fivejournals in accordance with inclusion criteria stated several associations betweenperiodontitis and COVID-19 severity, which consists of one cross sectional study,two cohorts, one case control, and one analytical retrospective study. COVID-19severity was measured based upon several parameters, which comprises of bloodparameters, biomarkers, hospitalization, mortality, ICU support, and ventilationassistance. Conclusion : Research methods used to discover the effects ofperiodontitis towards COVID-19 severity were case control, cohort, cross sectional,and analytical retrospective study. Periodontitis worsens COVID-19 severity byincreasing D-dimer, troponin, CRP, pro-BNP, procalcitonin, HbA1c, ferritin, andWBC, thus increasing hospitalization rate, mortality, ICU support, and ventilationassistance.