B Background : Every child experiences a different time of tooth eruption. There are various factors that can cause variations in the time of tooth eruption. There are still a lot of parents who still lack the knowledge about the factors that can delay the permanent tooth eruption in their children. Objective : The aim of this study was to find out the theoretical description of the problematic factors in inhibiting the eruption of permanent teeth in children. Methods : The study was conducted using a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) diagram through databases such as Google Scholar, PubMed, Wiley, and Science Direct using keywords of ((Permanent teeth) AND (teeth eruption) AND (factors influencing)) Results : 33 articles that fits the criteria found that the factors that influence the eruption of permanent teeth in children are environmental, genetic, racial and ethnic factors, and gender. Conclusion : Based on the results of the study, it can be concluded that there is a relationship between gender, race and ethnicity, genetics, and environmental factors such as nutrition and socioeconomic factors on the eruption time of permanent teeth in children aged 6-15 years.