O Office workers use a lot of electronic media in carrying out the primary functions of work, many jobs can cause work stress. Excessive computer use and work stress with the emergence of tension type headache (TTH). The purpose of this study is to determine the proportion and relationship of work stress and duration of computer use with TTH.METHODSCross-sectional study design, data collection was carried out in October – September 2021, at the STIAMI institute, covering 135 workers who were recruited using consecutive non-random sampling. The International Classification of Headache Disorder -3 (ICHD-3) guidelines were used to assess tension type headache and a health and safety executive questionnaire was used to assess work stress. Duration of computer use, length of work, and sociodemographic characteristics were collected using a questionnaire on the characteristics of the respondents. Data analysis used a simple logistic regression test, the limit of significance was p < 0.05.RESULTSThe median age was 26 (21 – 57) years, most of the subjects were male, namely 68 (50.4%), high work stress 82 (60.7%) subjects, duration of computer use 4 – 8 hours70 (51, 9%) subjects, the proportion of TTH 86 (63.7%) subjects. Simple logistic regression test showed work stress (OR = 16.8; 95%CI = 6.6 – 42.6; p <0.000), and duration of computer use (OR = 3.6; 95%CI = 1.7 – 7.6; p<0.001) is a risk factor that is significantly associated with TTH in workers.CONCLUSIONHigh work stress and duration of computer use 4 hours increase the risk of TTH in workers.