Fabrikasi dan karakterisasi membran Î²-tcp dengan menggunakan serbuk Î²-tcp, natrium alginat, dan kalsium klorida

DETAIL KOLEKSI

Fabrikasi dan karakterisasi membran Î²-tcp dengan menggunakan serbuk Î²-tcp, natrium alginat, dan kalsium klorida

Oleh : Muhammad Rian Gymnastiar

Info Katalog

Nomor Panggil : 617.695 MUH f

Penerbit : FKG - Usakti

Kota Terbit : Jakarta

Tahun Terbit : 2025

Pembimbing 1 : Eddy

Subyek : Dental materials

Kata Kunci : Î²-Tricalcium Phosphate, sodium alginate, calcium chloride, membrane, Guided Bone Regeneration

Status Posting : Published

Status : Lengkap

File Repositori

No.	Nama File	Hal.
1.	2025_SK_SIG_040002100084_Halaman-Judul.pdf	12
2.	2025_SK_SIG_040002100084_Surat-Pernyataan-Revisi-Terakhir.pdf	1
3.	2025_SK_SIG_040002100084_Surat-Hasil-Similaritas.pdf
4.	2025_SK_SIG_040002100084_Halaman-Pernyataan-Persetujuan-Publikasi-Tugas-Akhir-untuk-Kepentingan-Akademis.pdf
5.	2025_SK_SIG_040002100084_Lembar-Pengesahan.pdf
6.	2025_SK_SIG_040002100084_Pernyataan-Orisinalitas.pdf
7.	2025_SK_SIG_040002100084_Formulir-Persetujuan-Publikasi-Karya-Ilmiah.pdf
8.	2025_SK_SIG_040002100084_Bab-1.pdf	4
9.	2025_SK_SIG_040002100084_Bab-2.pdf	11
10.	2025_SK_SIG_040002100084_Bab-3.pdf	3
11.	2025_SK_SIG_040002100084_Bab-4.pdf	7
12.	2025_SK_SIG_040002100084_Bab-5.pdf	9
13.	2025_SK_SIG_040002100084_Bab-6.pdf	7
14.	2025_SK_SIG_040002100084_Bab-7.pdf	1
15.	2025_SK_SIG_040002100084_Daftar-Pustaka.pdf	6
16.	2025_SK_SIG_040002100084_Lampiran.pdf	9

Abstrak
Abstract

L Latar belakang: Î²-Tricalcium Phosphate (Î²-TCP) merupakan salah satu materialyang memiliki sifat osteokonduktif, bioaktif, dan biokompatibel sehinggaberpotensi digunakan sebagai filler pada membran untuk Guided BoneRegeneration (GBR). Penggunaan Natrium Alginat (NA), Kalsium Klorida (KK),dan Î²-TCP diharapkan dapat menghasilkan membran yang stabil dan efektif untukaplikasi regenerasi tulang. Tujuan: Untuk mengetahui karakteristik dan pengaruhvariasi konsentrasi Î²-TCP terhadap struktur kristal, gugus fungsi, dan morfologimembran yang difabrikasi. Metode: Penelitian eksperimental laboratoriumdeskriptif menggunakan campuran NA 2,5%, KK 1%, dan Î²-TCP dalam berbagaikonsentrasi (1%, 3%, 5%, dan 10%). Serbuk Î²-TCP difabrikasi denganmencampurkan kalsium karbonat (CaCOâ‚ƒ) dan Dibasic Calcium PhosphateDihydrate (DCPD) dengan rasio Ca/P 1,5 menggunakan ball mill, lalu dilakukanproses sintering pada suhu 1.100â„ƒ selama 6 jam (kenaikan suhu 10â„ƒ/menit).Karakterisasi membran dilakukan menggunakan X-Ray Diffraction (XRD), FourierTransform Infrared (FTIR), dan Scanning Electron Microscopy (SEM). Hasil:Pengamatan visual menunjukkan bahwa membran semakin kasar seiringpenambahan konsentrasi Î²-TCP. Hasil XRD menunjukkan bahwa struktur kristalÎ²-TCP tetap terdeteksi dalam membran meskipun sudah difabrikasi bersama NAdan KK, dengan puncak difraksi yang sesuai dengan pola Î²-TCP murni.Karakterisasi FTIR mengidentifikasi gugus fosfat, hidroksil, dan karbonil sebagaiciri khas Î²-TCP. Analisis SEM menunjukkan bahwa konsentrasi Î²-TCPberpengaruh pada kekasaran permukaan akibat aglomerasi partikel sehinggaberpotensi mempengaruhi kualitas membran. Kesimpulan: Membran Î²-TCP yangdifabrikasi memiliki potensi untuk digunakan sebagai GBR.Kata kunci: Î²-Tricalcium Phosphate, natrium alginat, kalsium klorida, membran,Guided Bone Regeneration.

B Background: Î²-Tricalcium Phosphate (Î²-TCP) is a material with osteoconductive,bioactive, and biocompatible properties, making it a potential filler material formembranes used in Guided Bone Regeneration (GBR). The use of Sodium Alginate(SA), Calcium Chloride (CC), and Î²-TCP is expected to produce a stable andeffective membrane for bone regeneration applications. Objective: To investigatethe characteristics and effects of varying Î²-TCP concentrations on the crystalstructure, functional groups, and morphology of the fabricated membranes.Methods: A descriptive experimental laboratory study was conducted using amixture of 2.5% SA, 1% CC, and Î²-TCP in various concentrations (1%, 3%, 5%,and 10%). The Î²-TCP powder was fabricated by mixing calcium carbonate(CaCOâ‚ƒ) and Dibasic Calcium Phosphate Dihydrate (DCPD) with a Ca/P ratio of1.5 using a ball mill, followed by a sintering process at 1,100â„ƒ for 6 hours(temperature increase of 10â„ƒ/minute). Membrane characterization was performedusing X-Ray Diffraction (XRD), Fourier Transform Infrared (FTIR), and ScanningElectron Microscopy (SEM). Results: Visual observations showed that themembrane surface became rougher with increasing Î²-TCP concentration. XRDresults indicated that the Î²-TCP crystal structure remained detectable in themembrane even after fabrication with NA and KK, with diffraction peaks consistentwith pure Î²-TCP patterns. FTIR characterization identified phosphate, hydroxyl,and carbonyl groups as characteristic features of Î²-TCP. SEM analysisdemonstrated that Î²-TCP concentration affected surface roughness due to particleagglomeration, potentially influencing membrane quality. Conclusion: Thefabricated Î²-TCP membrane has potential for use as GBR.Keywords: Î²-Tricalcium Phosphate, sodium alginate, calcium chloride,membrane, Guided Bone Regeneration.