S Subjects suffering from sinusitis with asthma often get severe headaches and post nasal drip if asthma relapse will aggravate and decrease the quality of life The results say that patients with sinusitis with asthma whose sinusitis get treatment found a pretty good improvement on asthma.But other studies say this is unrelated because there is no improvement in lung function in sinusitis patients with asthma performed BSEF surgery in sinus patients, In Indonesia not many have studied about this relationship. It is hoped that by knowing this relationship the patient with sinusitis with asthma can get treatment on sinusitis so that exacerbation of asthma is reduced. The method used in this study is by cross sectional with 120 respondents aged 17-55 years in ENT clinic RSUD Budhi Asih, East Jakarta. Data were taken by conducting interviews and physical examination of sinusitis performed by otolaryngologist specialists. Data analysis was performed using Statistical Pakage for Social Science (SPSS) program with significance level less than 0.05. The analysis using Chi-Square test showed there was a significant correlation between sinusitis and asthma, and there was no significant correlation between sinusitis and asthma to age in the age group 17-55 years. This study shows the relationship between sinusitis with asthma at the age of 17-55 years.