T This research background with changes in the spatial structure and spatial patternof Palembang City at this time which has left the river as a yard front with the aimof studying changes in the structure and spatial pattern of the City of Palembangfor the period 1917 - 2020. The structure and spatial pattern are viewed from theaspect of the location of the center of activity (government), the location of thecenter of city facilities, transportation networks, the area of built-up land and theshape of the city. The analysis technique used in this research is overlaysuperimpose and descriptive. The results of the analysis show that in the period1945 – 1984, the spatial structure monocentric and there was a change in thespatial structure which was originally centered on Fort Kuto Besak to shift towardsthe mainland with a new center of government. The spatial pattern that wasoriginally a patternlinear extends following the river, turning into fan shaped citiesby following the development of the arterial road network with a growth rate of26% of built-up land. The period 2000 – 2020 is a period commencing changes inthe spatial structure and spatial pattern of the second for Palembang City wherethe spatial structure of Palembang city was before monocentric transformed intomulti centered with spatial pattern already fully becoming fan shaped cities. Basedon the 2012 – 2032 RTRW directions for Palembang City and a review of existingconditions, the spatial structure of Palembang City is in accordance with the RTRWdirectives and the spatial structure has become multi centered with stipulated PPKJakabaring. However, based on the results of the analysis, there are 3 Sub-PPKthat have not yet developed, namely Gandus District, Sebatang Borang District andSeberang Ulu District followed by the underdeveloped land transportation, whilethe spatial pattern of Palembang City is in accordance with the directions ofPalembang City's RTRW.