T The goal of this study to analyze an impact of Labour, Aglommeration, HumanDevelopment Index, Gross Regional Domestic Bruto Per Capita and Investmenton Inequality between regions using Willamson Index in six provinces in javaisland. The data used in this reasearch is secondary data derived from thepublication of Badan Pusat Statistik in the form of annual data from 2013 to2017. Analysis method that used is panel data regression with the number ofobjects 6 Provinces in Java Island. The results of this study indicate that theHuman Development Index, Gross Regional Domestic Bruto Per Capita andInvestment have a significant effect on Inequality between regions in Java Islandand Labour and Aglommeration does not have a significant influence onInequality between regions in Java Island.