S Smokers are at risk of suffering from COPD or lung cancer ranging from 20-25%. The relationship between smoking habits and COPD is a dose response relationship, which means that the more cigarettes smoked frequently, will cause the risk of COPD greater. The problem of exacerbations has been proven to adversely affect the quality of patient’s life, worsen the patient’s inflammation on the road and systemic. This study was an observational analytic study with a cross-sectional approach, to determine the correlation of smoking with the frequency of COPD exacerbations. The research location has been conducted at Budhi Asih Hospital, East Jakarta. Selection of research subjects as samples of this study was carried out with a consecutive non random sampling technique. Data analysis was performed by Spearman correlation test using SPSS version 25 program with p -0.001 (p <0.05) which showed that there was a correlation between smoking and the frequency of COPD exacerbations. In this study, majority of patients with a history of heavy smokers (66.7%) with a median Brinkman index of 848 cigarette with a minimum of 5 and a maximum of 3840 more likely to be exacerbated by COPD shows that the frequency of exacerbations is based on total CCQ with a median of 1.30. The correlation value of smoking with the frequency of COPD exacerbations p <0.001 with a weak Spearman correlation value.