A Academic achievement is a learning result obtained from learning activities in school. The Ministry of National Education Research and Development Research produced findings that in the leading 20SMA in Indonesia there were 21.75% of students with average intelligence levels who had achievements below the average. One of the factors that can affect academic achievement is depression. This study aims to determine the relationship between the level of depression and academic achievement. This study used an observational analytic design with cross sectional method which included 191 10th and 11th grade students at SMAN 8 Jakarta. Data collected by using secondary data in the form of report cards and primary data in the form of a questionnaire covering the level of depression and the level of education of parents. Data analysis using SPSS version 20.0 and the level of significance used at 0.05. From the results of the analysis using Chi-square and Kolmogorov-Smirnov tests showed there was no relationship between the level of depression (p = 0.612) and the level of education of parents (p = 1,000) with academic achievement. There is no relationship between the level of depression and academic achievement.