Karakterisasi komposit β-trikalsium fosfat dari batu kapur dengan asam poliakrilat sebagai kandidat bone graft
Nomor Panggil : 617.695 DIA k
Penerbit : FKG - Usakti
Kota Terbit : Jakarta
Tahun Terbit : 2025
Pembimbing 1 : Tansza Permata Setiana Putri
Subyek : Dental materials
Kata Kunci : β-TCP, LIMESTONE, POLYACRYLIC ACID, COMPOSITE, BONE GRAFT, POROSITY, DTS
Status Posting : Published
Status : Lengkap
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1. | 2025_SK_SIG_040002100039_Halaman-Judul.pdf | 17 | |
2. | 2025_SK_SIG_040002100039_Surat-Pernyataan-Revisi-Terakhir.pdf | 1 | |
3. | 2025_SK_SIG_040002100039_Surat-Hasil-Similaritas.pdf | 1 | |
4. | 2025_SK_SIG_040002100039_Halaman-Pernyataan-Persetujuan-Publikasi-Tugas-Akhir-untuk-Kepentingan-Akademis.pdf | 1 | |
5. | 2025_SK_SIG_040002100039_Lembar-Pengesahan.pdf | 1 | |
6. | 2025_SK_SIG_040002100039_Pernyataan-Orisinalitas.pdf | 1 | |
7. | 2025_SK_SIG_040002100039_Formulir-Persetujuan-Publikasi-Karya-Ilmiah.pdf | 1 | |
8. | 2025_SK_SIG_040002100039_Bab-1.pdf | 5 | |
9. | 2025_SK_SIG_040002100039_Bab-2.pdf | 9 |
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10. | 2025_SK_SIG_040002100039_Bab-3.pdf | 4 |
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11. | 2025_SK_SIG_040002100039_Bab-4.pdf | 11 |
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12. | 2025_SK_SIG_040002100039_Bab-5.pdf | 13 |
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13. | 2025_SK_SIG_040002100039_Bab-6.pdf | 6 |
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14. | 2025_SK_SIG_040002100039_Bab-7.pdf | 1 | |
15. | 2025_SK_SIG_040002100039_Daftar-Pustaka.pdf | 7 | |
16. | 2025_SK_SIG_040002100039_Lampiran.pdf | 26 |
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L Latar belakang: Bone graft adalah teknik yang umum digunakan dalam kedokteran gigi untuk memperbaiki defek tulang. Beta trikalsium fosfat (β-TCP) berbahan dasar batu kapur dapat dimanfaatkan dan berpotensi menjadi alternatif material bone graft dengan dicampur asam poliakrilat (PAA) untuk mendapatkan granul komposit. Tujuan: Untuk mengetahui karakteristik blok dan granul komposit dari campuran βTCP batu kapur dan PAA, serta pengaruh komposisi campurannya terhadap karakteristik tersebut. Metode: Jenis penelitian ini adalah penelitian eksperimental laboratorik dengan desain post-test only control group. Kelompok yang diteliti terdiri dari kontrol negatif (bubuk PAA murni), kontrol positif (PAA + β-TCP komersil), dan tiga kelompok perlakuan dengan variasi campuran β-TCP batu kapur dan PAA: 60:40, 50:50, dan 40:60 (%w/w). Karakterisasi dilakukan dengan uji porositas, Diametral Tensile Strength (DTS), dan Scanning Electron Microscope (SEM). Hasil: β-TCP berbahan batu kapur menghasilkan komposit dengan porositas dan DTS lebih tinggi dibandingkan PAA murni dan β-TCP komersil. Semakin tinggi komposisi β-TCP, semakin besar nilai porositas dan DTS. Blok komposit banyak membentuk porositas tertutup (closed porosity) dengan ukuran rata-rata makroporus 133,70–198,40 µm, serta didapatkan granul dengan ukuran rata-rata 512,80–788,80 µm dengan mikroporus kurang dari 5 µm. Kesimpulan: Komposit campuran β-TCP berbahan batu kapur dengan PAA berpotensi digunakan sebagai kandidat bone graft dan komposisi campurannya berpengaruh terhadap karakteristik blok dan granul komposit tersebut, namun masih memerlukan optimasi. Kata kunci: β-TCP, batu kapur, asam poliakrilat, komposit, bone graft, porositas, DTS.
B Background: Bone grafting is a widely used technique in dentistry to repair bone defects. Limestone-based beta-tricalcium phosphate (β-TCP) holds potential as an alternative bone graft material when combined with polyacrylic acid (PAA) to produce composite granules. Objectives: To determine the characteristics of block and granular composites made from limestone-based β-TCP and PAA, as well as the effect of their composition on these characteristics. Methods: This study is a laboratory experimental research with a post-test only control group design. The study groups include a negative control (pure PAA powder), a positive control (PAA + commercial β-TCP), and three treatment groups with variations in the mixture of limestone β-TCP and PAA: 60:40, 50:50, and 40:60 (%w/w). Characterization was carried out using porosity measurement, Diametral Tensile Strength (DTS), and Scanning Electron Microscopy (SEM). Results: Limestone-based β-TCP produced composites with higher porosity and DTS compared to pure PAA samples and commercial β-TCP. As the β-TCP composition increased, both porosity and DTS values also increased. The composite blocks predominantly formed closed porosity, with an average macro-pore size of 133.70–198.40 µm. Granules had an average size of 512.80–788.80 µm with micropores smaller than 5 µm. Conclusion: The composite mixture of limestone-based beta-tricalcium phosphate (β-TCP) and polyacrylic acid (PAA) shows potential as a bone graft candidate, with its composition significantly influencing the characteristics of the composite blocks and granules. However, further optimization is still required. Keywords: β-TCP, limestone, polyacrylic acid, composite, bone graft, porosity, DTS.