A About 65% of all lymphatic filariasis can be found in South East Asia, including Indonesi. As one of neglected tropical diseases (NTDs), Lymphatic filariasis has a major problem on public health sector in Indonesia. The data from Indonesian Ministry of Health reported that around 125 million people live in 337 endemic districts area and 11.000 peoples were suffered with hydrocele and elephantiasis. The clinical manifestation has a major impact not just social and economic burden, but also decreasing the quality of life. tThis research was conducted to explore the epidemiology of lymphatic filariasis in rural area. An observational, croos-sectional study was conducted among 64 subjects from March to May 2014. The diagnosis of infection was confirmed by finger prick test, which was done from 10 pm until 2 am. By using a standardized questionnaire, all of the subjects were asked about their characteristic. The prevalence of LF was 100%, all of 64 subjects were positive with microfilaria and the result count varies from 3 up-to 34 microfilaria. All of the subjects ar genous inhabitants who engaged at the rubber plantation site from 6 am to 12 pm, and close contact with mosquitoes bite. These two districts became a potential endemic area, because the districts were surrounded by tendemic area and never had mass drug administration (MDA) before. The possibility of vector transmission at the plantation are Mansonia or Anopheles or due to migration of the inhabitants from the surrounding endemic area to these two districts. The rubber plantation site has played a major role as inbreeding site of the vector. Based on this study, we need to modify the host, agent and environment factors to break off the chain of lymphatic filariasis transmission at the endemic area